The Claim
Administration of 17-α-estradiol at 14.4 parts per million in the diet to male UM-HET3 mice beginning at 16 months of age was associated with a 19% increase in median lifespan (p<0.0001, log-rank test), representing the largest effect size among tested interventions.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Scientists fed old male mice a special chemical called 17-α-estradiol and found they lived about 19% longer than mice that didn't get the chemical.
See the scientific wording
17-α-estradiol (14.4 ppm in diet) administered to male UM-HET3 mice beginning at 16 months of age was associated with a 19% increase in median lifespan (p<0.0001, log-rank test), representing the largest effect size among tested interventions
What the research says
1 studyThe study gave the same drug (17-α-estradiol) at the same dose to the same type of male mice starting at the same age as the claim describes, and found exactly the same result: a 19% increase in median lifespan with high statistical significance. It also tested other drugs that didn't work, confirming this was the most effective treatment.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.