Giving mice thyroxine for three weeks raises their body temperature by 1–2°C, and even when placed in cold environments, they maintain this higher temperature — indicating their bodies are actively...

Pro

Against

Evidence from Studies

Supporting (1)

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At thermoneutrality, acute thyroxine-induced thermogenesis and pyrexia are independent of UCP1

Case-Control Study

Animal

2019 Jul

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

At thermoneutrality, acute thyroxine-induced thermogenesis and pyrexia are independent of UCP1

Score: 13

DOI: 10.1016/j.molmet.2019.05.005