Taking one pill of a thyroid hormone called T3 might cause older men to temporarily produce more testosterone and a related hormone, which could help explain why thyroid and sex hormones might be connected as men age.

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Pro

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Evidence from Studies

Supporting (1)

40

Community contributions welcome

40

Effect of Thyroid Status Modulation on Pituitary and Peripheral Hormone Concentrations in Healthy Older Subjects

Cross-Sectional Study

Human

2025

Scientists gave older men a single pill of a thyroid hormone (T3) and found that their testosterone and SHBG levels went up by about 12-14% within four days — exactly what the claim said.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Effect of Thyroid Status Modulation on Pituitary and Peripheral Hormone Concentrations in Healthy Older Subjects

Score: 40

DOI: 10.1159/000542832

Similar Assertions

When healthy older men take a single pill of a thyroid hormone called T3, their body makes more of a hormone that tells the testes to work harder — but another hormone called TSH doesn’t do this, which suggests T3 has a special role in controlling this process.

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