Medications called GLP-1 receptor agonists are associated with a reduction in the number of calories consumed each day by 16% to 39% in human individuals.

Medications that mimic a gut hormone called GLP-1 can make people feel less hungry, eat less food, and lose body fat over time.

GLP-1 receptor agonists trigger changes in the body that occur even when weight loss is accounted for, suggesting these drugs have effects beyond reducing body weight.

Losing weight by turning on a specific brain and gut signal (GLP-1) can help improve health problems linked to obesity, like high blood sugar or high blood pressure.

These diabetes and weight-loss drugs might help prevent or lessen health problems caused by obesity, like heart disease or diabetes.

A type of diabetes drug called GLP-1 agonists might help people with fatty liver disease by reducing liver fat, improving blood sugar, and helping with weight loss—based on early study results.