The Claim

In patients undergoing hemodialysis, daily oral supplementation with 5 grams of creatine monohydrate over a 12-month period leads to a statistically significant increase in fat-free mass compared to placebo, with a higher proportion of supplemented individuals showing gains (60%) relative to the control group (36.8%), suggesting creatine may help reduce muscle loss in chronic kidney disease.

Source: Effect of Creatine Supplementation on Body Composition and Malnutrition-Inflammation Score in Hemodialysis Patients: An Exploratory 1-Year, Balanced, Double-Blind Design

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
74score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Taking a creatine supplement every day might help kidney patients on dialysis keep more muscle mass over time.

See the scientific wording

In hemodialysis patients, daily oral supplementation with 5 grams of creatine monohydrate for 12 months increases fat-free mass by a statistically significant amount compared to placebo, with 60% of supplemented patients showing gains versus 36.8% in the control group, indicating a potential role for creatine in mitigating muscle loss associated with chronic kidney disease.

What the research says

1 study
  1. Study: Effect of Creatine Supplementation on Body Composition and Malnutrition-Inflammation Score in Hemodialysis Patients: An Exploratory 1-Year, Balanced, Double-Blind Design

    The study gave creatine to dialysis patients for a year and found they gained more muscle mass than those who didn’t, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.