mechanistic
Analysis v1
Strong Support
For people who are overweight (BMI 23 or higher), high blood pressure is responsible for about 1 in 5 of the extra heart attack and stroke risk — it’s the second biggest reason after diabetes that extra weight leads to heart problems.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Causal relationship of excess body weight on cardiovascular events through risk factors
Cohort Study
Human
2022 Mar 28This study found that being overweight (BMI ≥23) increases heart attack and stroke risk mostly through diabetes and high blood pressure, and high blood pressure alone explains about 22% of that risk — just like the claim says.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.