The Claim
High-temperature cooking of carbohydrate- and protein-rich foods generates advanced glycation end products that induce systemic inflammation.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Cooking carbohydrate- and protein-rich foods at high temperatures produces compounds called advanced glycation end products that trigger systemic inflammation.
See the scientific wording
High-temperature cooking of carbohydrate- and protein-rich foods generates advanced glycation end products that induce systemic inflammation.
When food is cooked at high heat, harmful chemicals called AGEs form and enter the body. These chemicals attach to a receptor on immune cells called RAGE, which turns on a signaling system that releases inflammatory chemicals. This causes widespread inflammation throughout the body, especially in the liver and lungs, and also reduces the ability of immune cells to clean up harmful particles.
What the research says
3 studiesWhen people cook meat or carbs at high heat, it creates harmful chemicals called AGEs. This study showed that when people ate less of these chemicals by using gentler cooking methods, their body’s inflammation levels went down.
When food is cooked at high heat, it makes chemicals called AGEs that can trigger inflammation in the body. This study showed that these same chemicals cause immune cells in the lungs to release inflammation signals, proving they can make the body more inflamed.
Study: Acrylamide and Advanced Glycation End Products in Frying Food: Formation, Effects, and Harmfulness
When you fry foods like potatoes or meat at high heat, harmful chemicals called AGEs form, and this study shows those chemicals can cause body-wide inflammation.
Related videos
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 3 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.