descriptive
Analysis v1
9
0
Higher levels of uric acid made blood vessels less able to widen in response to a chemical signal, which could affect blood flow. This finding is from the abstract summary - full study details were not available
Scientific Claim
Uric acid was associated with reduced vasodilatory response of aortic artery rings to acetylcholine in a dose-dependent manner.
Original Statement
“uric acid dose dependently inhibited endothelial function as manifested by a reduced vasodilatory response of aortic artery rings to acetylcholine”
Evidence Quality Assessment
Claim Status
overstated
Study Design Support
Design cannot support claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The abstract uses 'inhibited', implying causation, but the study design only supports associative claims.
Evidence from Studies
Supporting (1)
9
9
A causal role for uric acid in fructose-induced metabolic syndrome.
Cohort Study
Animal
2006 MarContradicting (0)
0
No contradicting evidence found