HIV patients with belly fat who responded to tesamorelin had more lean muscle mass in all four trunk muscles, with increases between 0.64 and 1.08 cm² compared to placebo after 26 weeks.

HIV patients with belly fat who responded to tesamorelin saw better lean muscle quality in their abdominal and rectus muscles, with improvements of 1.39 and 1.78 units respectively compared to placebo after 26 weeks.

For HIV patients with belly fat who responded to this drug, taking tesamorelin for 6 months made their trunk muscles less fatty and more dense, like turning soft muscle into firmer muscle.

This drug didn’t just make muscles less fatty—it also made them bigger in size, adding about half a square inch of lean muscle in the core area after six months.

For HIV patients with belly fat who responded to tesamorelin, the drug was linked to better muscle density in four trunk muscles, with improvements between 1.56 and 4.86 units compared to placebo after 26 weeks.

HIV patients with belly fat who responded to tesamorelin had bigger rectus and psoas muscles (0.44 and 0.46 cm² larger) compared to placebo after 26 weeks.