If scientists find a simple test that shows who will lower their 'bad' cholesterol a lot when they eat more saturated fat, doctors could give personalized diet advice to help people keep their hearts healthy.

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Evidence from Studies

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Does variation in serum LDL-cholesterol response to dietary fatty acids help explain the controversy over fat quality and cardiovascular disease risk?

Narrative Review

2021 Jul

This study says some people’s bad cholesterol drops a lot when they eat less saturated fat, while others don’t change much — and if we could find an easy test to spot who responds well, we could give better, personalized diet advice.

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Does variation in serum LDL-cholesterol response to dietary fatty acids help explain the controversy over fat quality and cardiovascular disease risk?

Score: 1

DOI: 10.1016/j.atherosclerosis.2021.03.024

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If scientists could find a simple test—like a blood check—that tells who’s likely to have bad cholesterol rise when they eat fatty foods, then doctors could give personalized diet advice to help protect hearts.

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