If you try to use a simple model that only accounts for fast-growing cancers to analyze data that also includes slow-growing ones, you’ll wrongly think the fast-growing cancers start earlier and last longer than they really do.

Evidence from Studies

Supporting (1)

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Identification of the Fraction of Indolent Tumors and Associated Overdiagnosis in Breast Cancer Screening Trials

Computational/Algorithm Study

2019 Jan 1

If you pretend all breast cancers will grow and cause harm (ignoring the ones that won’t), you’ll wrongly think they grow faster and take longer to show up — and this study proves that’s exactly what happens.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Identification of the Fraction of Indolent Tumors and Associated Overdiagnosis in Breast Cancer Screening Trials

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DOI: 10.1093/aje/kwy214

Similar Assertions

If you try to use a simple model that assumes all tumors grow quickly to explain data that includes both fast-growing and slow-growing tumors, you’ll wrongly think cancer starts earlier and grows faster than it really does.

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