The Claim
All-trans-retinoic acid and vitamin D₃ inhibit leptin secretion from human omental adipose tissue in vitro, with all-trans-retinoic acid demonstrating potent inhibitory effects and vitamin D₃ exhibiting powerful inhibition that is synergistic with all-trans-retinoic acid.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Two vitamins—retinoic acid and vitamin D3—can reduce the amount of a fat hormone called leptin in human fat tissue in a lab dish, and when used together, they work even better than alone.
See the scientific wording
Retinoic acid and vitamin D₃ inhibit leptin secretion from human omental adipose tissue in vitro, with all-trans-retinoic acid showing potent effects and vitamin D₃ showing powerful inhibition that is synergistic with all-trans-retinoic acid.
What the research says
1 studyStudy: Retinoic acid and vitamin D(3) powerfully inhibit in vitro leptin secretion by human adipose tissue.
The study found that two vitamins — retinoic acid and vitamin D3 — reduce the production of a fat hormone called leptin in human fat tissue in the lab, and when used together, they work even better. This matches exactly what the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.