Two vitamins—retinoic acid and vitamin D3—can reduce the amount of a fat hormone called leptin in human fat tissue in a lab dish, and when used together, they work even better than alone.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

21

Retinoic acid and vitamin D(3) powerfully inhibit in vitro leptin secretion by human adipose tissue.

Cross-Sectional Study

Human

2001 Aug

The study found that two vitamins — retinoic acid and vitamin D3 — reduce the production of a fat hormone called leptin in human fat tissue in the lab, and when used together, they work even better. This matches exactly what the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Retinoic acid and vitamin D(3) powerfully inhibit in vitro leptin secretion by human adipose tissue.

Score: 21

DOI: 10.1677/JOE.0.1700425

Similar Assertions

Two vitamins—retinoic acid and vitamin D3—can reduce the amount of a hormone called leptin that fat tissue releases, and when used together, they work even better than alone.

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Taking vitamin D might help your body release a hormone that tells you when you're full and also stop a protein that blocks muscle growth, so you could feel more energized and build muscle more easily.

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When you have more vitamin D in your body, your fat cells send out more of a signal called leptin, which tells your brain you’re full and don’t need to store more fat—so you might gain less fat over time.

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72%