The Claim
All-trans-retinoic acid and vitamin D3 inhibit leptin secretion from human omental adipose tissue in vitro, with all-trans-retinoic acid demonstrating potent inhibitory effects and vitamin D3 exhibiting powerful inhibition that is synergistic with all-trans-retinoic acid.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Two vitamins—retinoic acid and vitamin D3—can reduce the amount of a hormone called leptin that fat tissue releases, and when used together, they work even better than alone.
See the scientific wording
Retinoic acid and vitamin D3 inhibit leptin secretion from human omental adipose tissue in vitro, with all-trans-retinoic acid showing potent effects and vitamin D3 showing powerful inhibition that is synergistic with all-trans-retinoic acid.
What the research says
1 studyStudy: Retinoic acid and vitamin D(3) powerfully inhibit in vitro leptin secretion by human adipose tissue.
Scientists tested two vitamins — retinoic acid and vitamin D3 — on fat tissue from humans in a lab dish and found that both reduced the hormone leptin, and when used together, they worked even better. This matches exactly what the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.