The Claim
In a simulated human colon system (SHIME®), supplementation with 2.6 g/day of pomegranate extract for one week is associated with decreased abundance of Prevotella in the ascending and transverse colon and reduced propionate production in the transverse colon.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When pomegranate extract is added to a lab model of the human colon, the abundance of Prevotella bacteria decreases in the ascending and transverse colon, and propionate production decreases in the transverse colon.
See the scientific wording
In a simulated human colon system (SHIME®), supplementation with 2.6 g/day of pomegranate extract for one week was associated with decreased abundance of Prevotella in the ascending and transverse colon, potentially linked to reduced propionate production in the transverse colon.
Pomegranate compounds break down in the colon into molecules that kill or slow down certain bacteria called Prevotella. Fewer Prevotella bacteria mean less propionate acid is made in the middle part of the colon.
What the research says
1 studyStudy: Gut Microbiota Modulation by Pomegranate Extract: Insights from a Controlled Supplementation Study
In a lab model of the human colon, taking pomegranate extract for a week lowered a type of gut bacteria called Prevotella, and this drop was linked to less of a healthy acid (propionate) being made in that part of the colon.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.