The Claim
The human type 2 iodothyronine deiodinase (D2) enzyme in the MSTO-211H mesothelioma cell line is encoded by the hDio2 gene and is a selenoprotein, as confirmed by immunoprecipitation of a 31-kDa (75)Se-labeled protein using an antibody against a peptide derived from the hDio2 mRNA sequence.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In the MSTO-211H mesothelioma cell line, the D2 enzyme is produced from the hDio2 gene and contains selenium, as demonstrated by the binding of a selenium-labeled protein to an antibody targeting a sequence from the hDio2 gene.
See the scientific wording
The human type 2 iodothyronine deiodinase (D2) enzyme in the MSTO-211H mesothelioma cell line is encoded by the hDio2 gene and is a selenoprotein, as confirmed by immunoprecipitation of a 31-kDa (75)Se-labeled protein using an antibody against a peptide derived from the hDio2 mRNA sequence.
The body builds a selenium-containing enzyme from a specific gene, which activates thyroid hormone; this enzyme is constantly broken down by a cellular cleanup system, but its levels rise when selenium is available or when the cleanup system is blocked.
What the research says
1 studyScientists found that in a specific cancer cell, the enzyme that turns thyroid hormone into its active form is made from a gene called hDio2 and contains selenium, which they proved by tagging the enzyme with a radioactive form of selenium and catching it with a special antibody — just like the claim said.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.