The Claim
Among adults with overweight and obesity, elevated plasma levels of erythritol, erythronate, mannitol-sorbitol, and arabitol-xylitol are positively associated with estimated 10-year cardiovascular disease risk, while saccharin shows a weaker positive association and acesulfame shows no association.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In adults with overweight or obesity, higher blood levels of certain sugar alcohols like erythritol and related compounds are linked to a higher estimated risk of cardiovascular disease over 10 years; saccharin shows a weaker link, and acesulfame shows no link.
See the scientific wording
Among adults with overweight and obesity, plasma levels of erythritol and other sugar alcohols such as erythronate, mannitol-sorbitol, and arabitol-xylitol are positively associated with estimated 10-year cardiovascular disease risk, while saccharin shows a weaker association and acesulfame shows no association.
High levels of erythritol and related sugar alcohols in the blood damage the lining of blood vessels and trigger widespread inflammation, which speeds up the buildup of plaque in arteries and raises the risk of heart disease.
What the research says
1 studyIn people with extra weight, higher blood levels of certain sugar-free sweeteners like erythritol were linked to a higher chance of heart disease. When people lost weight through diet, their blood levels of these sweeteners dropped — and so did their heart disease risk. This supports the idea that these substances are tied to heart health.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.