The Claim
MF-300 at 10 mg/kg administered orally for 12 weeks increases the contraction rate of the extensor digitorum longus muscle by 8.7% in aged mice, demonstrating a selective effect on fast-twitch fiber function that is independent of changes in muscle mass.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In aged mice, a 12-week treatment with MF-300 at 10 mg/kg increases the contraction rate of the extensor digitorum longus muscle by 8.7% without changing muscle mass, indicating a specific effect on fast-twitch muscle fibers.
See the scientific wording
MF-300 at 10 mg/kg significantly improves the contraction rate of the extensor digitorum longus (a fast-twitch muscle) by 8.7% in aged mice after 12 weeks of treatment, indicating a selective effect on fast-twitch fiber function independent of muscle mass.
A molecule that blocks the breakdown of a signaling chemical called PGE2 allows more of it to build up in old muscle. This chemical directly improves how quickly and strongly the fast-twitch muscle fibers can contract by making their internal machinery work more efficiently, without changing the size of the muscle.
What the research says
1 studyIn old mice, a pill called MF-300 made their fast-twitch muscles contract faster—without making the muscles bigger—just like the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.