Eating or being exposed to the artificial sweetener Acesulfame Potassium might cause the body to release more inflammatory signals in animals, which could affect the uterus in a way that leads to inflammation.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

40

Consumption of Artificial Sweetener Acesulfame Potassium Increases Preterm Risk and Uterine Contraction with Calcium Influx increased via Myosin Light Chain kinase - myosin Light Chain 20 related Signaling Pathway.

Cohort Study

Human

2022 Oct

This study found that a sugar-free sweetener called Acesulfame Potassium makes the uterus contract more and releases more inflammatory signals in animals — exactly what the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Consumption of Artificial Sweetener Acesulfame Potassium Increases Preterm Risk and Uterine Contraction with Calcium Influx increased via Myosin Light Chain kinase - myosin Light Chain 20 related Signaling Pathway.

Score: 40

DOI: 10.1002/mnfr.202200298

Similar Assertions

Studies on animals suggest that if they’re given a lot of Acesulfame Potassium over a long time, their uteruses contract more strongly and the proteins that control those contractions change in some way.

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When rats and mice are given a lot of acesulfame potassium (an artificial sweetener), their guts and livers show more signs of inflammation, but if they get only a little or are in a different setup, no inflammation shows up—suggesting there’s a limit to when it causes problems.

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