In healthy people, most of the active thyroid hormone in the blood comes from the conversion of a precursor hormone in tissues outside the thyroid gland, not from the thyroid gland itself. This...

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Peripheral metabolism of thyroid hormones in man. I. Direct measurement of the conversion rate of thyroxine to 3,5,3'-triiodothyronine (T3) and determination of the peripheral and thyroidal production of T3.

Cross-Sectional Study

Human

1983 Jun

Contradicting (0)

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Peripheral metabolism of thyroid hormones in man. I. Direct measurement of the conversion rate of thyroxine to 3,5,3'-triiodothyronine (T3) and determination of the peripheral and thyroidal production of T3.

Score: 47

DOI: 10.1210/JCEM-56-6-1152