The Claim
A single 16-hour overnight fast does not increase the rate of incorporation of dietary protein-derived amino acids into skeletal muscle protein in healthy young adult men, as measured by postprandial [1-13C]phenylalanine enrichment in myofibrillar protein, despite a modest reduction in insulin response.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In healthy young adult men, a 16-hour overnight fast does not increase how quickly amino acids from food are added to muscle protein, even though insulin levels drop slightly after eating.
See the scientific wording
A single 16-hour overnight fast does not increase the rate at which dietary protein-derived amino acids are incorporated into skeletal muscle protein in healthy young adult men, as measured by postprandial [1-13C]phenylalanine enrichment in myofibrillar protein, despite a modest reduction in insulin response.
After a 16-hour fast, the body releases less insulin when eating, but this lower insulin level does not make muscle cells take up or use amino acids from food any faster to build new muscle protein.
What the research says
1 studyEven when healthy young men fasted for 16 hours instead of 10, their muscles didn’t use the protein from their next meal any better to build muscle—despite having lower insulin levels. So, longer fasting didn’t help.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.