In kids who don’t have diabetes or anemia, red blood cell creatine doesn’t seem to track with average blood sugar levels, so it might not be a good way to measure sugar exposure over time.

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Pro

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Against

Evidence from Studies

Supporting (1)

36

Community contributions welcome

36

Elevation of erythrocyte creatine post-puberty unrelated to erythrocyte lifespan: Implications from the lack of correlation between HbA1c and erythrocyte creatine.

Cross-Sectional Study

Human

2025 Feb 15

The study found that in kids without diabetes or anemia, red blood cell creatine doesn’t strongly link to HbA1c, which matches the claim. This means EC might not be a good measure of blood sugar in these children.

Contradicting (0)

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No contradicting evidence found

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Source Study

Elevation of erythrocyte creatine post-puberty unrelated to erythrocyte lifespan: Implications from the lack of correlation between HbA1c and erythrocyte creatine.

Score: 36

DOI: 10.1016/j.cca.2025.120130

Similar Assertions

In teenage girls who don’t have diabetes or anemia, red blood cell creatine goes up as they get older, especially after puberty—but this doesn’t happen in boys. This rise isn’t linked to blood sugar levels.

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In pregnant women without diabetes, having more hemoglobin in the blood is linked to slightly higher HbA1c levels — a marker usually tied to blood sugar — suggesting that blood cell levels might affect this test even if sugar isn't high.

37

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Girls who have started their periods tend to have higher levels of creatine in their red blood cells compared to those who haven’t, and this doesn’t seem to be because of differences in blood sugar control.

36

0

72%

In pregnant women without diabetes, having more red blood cells might make their blood sugar test results look higher than they really are, even if their actual sugar levels are normal.

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70%