The Claim

In resistance-trained men, 8 weeks of creatine supplementation combined with resistance training increases skeletal muscle mass and intracellular water, but does not alter the ratio between skeletal muscle mass and intracellular water, indicating that muscle growth from creatine supplementation occurs without a disproportionate increase in cellular hydration relative to muscle gain.

Source: Creatine Supplementation Does Not Influence the Ratio Between Intracellular Water and Skeletal Muscle Mass in Resistance-Trained Men.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
38score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

If you're a guy who lifts weights, taking creatine for 8 weeks can help you gain muscle and hold more water inside your muscle cells — but the water doesn't increase more than the muscle does, so it's not just 'bloating' — it's real growth.

See the scientific wording

In resistance-trained men, 8 weeks of creatine supplementation combined with resistance training increases skeletal muscle mass and intracellular water, but does not alter the ratio between skeletal muscle mass and intracellular water, suggesting that muscle growth from creatine occurs without disproportionate cellular hydration relative to muscle gain.

What the research says

1 study
  1. Study: Creatine Supplementation Does Not Influence the Ratio Between Intracellular Water and Skeletal Muscle Mass in Resistance-Trained Men.

    The study found that when men took creatine and lifted weights, their muscles grew and their muscle cells held more water, but the balance between muscle size and water stayed the same—just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.