quantitative
Analysis v1
Strong Support
In fat mice with fatty liver, the liver cells have fewer 'acidic cleanup pockets' than healthy mice, which might mean their cells aren't cleaning themselves properly.
10
0
Evidence from Studies
Supporting (1)
10
Community contributions welcome
10
Inhibition of mTOR improves the impairment of acidification in autophagic vesicles caused by hepatic steatosis.
Cross-Sectional Study
Animal
2016 Jan 22The study found the same thing as claimed: liver cells from fatty liver mice have much lower levels of acidic 'digestion pockets' than healthy mice, which means their cleanup process isn't working well.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.