assertion
14
Pro
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Against

When fat cells get inflamed and stressed, they don't respond to signals properly, making it harder to lose fat. NAC can help reduce this inflammation and improve fat loss.

Scientific Claim

In obesity, adipose tissue inflammation and oxidative stress impair insulin signaling, leading to reduced fat loss efficiency; NAC supplementation reduces inflammatory markers and oxidative stress in adipose tissue, improving metabolic function.

Original Statement

Fat loss doesn't stall because calories suddenly stopped working. It stalls because fat cells stop responding correctly to signals. If you watch my channel a lot, this is something I say frequently, okay? in obesity and in like stubborn belly fat scenarios, fat tissue becomes inflamed, reactive oxygen species increase, insulin signaling becomes distorted. And there was a study that was published in pharmaceutical research. It looked at this like pretty much directly. Okay, it was rodent model. They gave mice a highfat diet, but they were given NAC in their drinking water for 11 weeks. The NAC treated mice gained roughly half as much weight as the highfat diet mice without NAC, 22% versus 47%.

Context Details

Domain

nutrition

Population

animal

Subject

adipose tissue inflammation and oxidative stress

Action

impair

Target

insulin signaling and fat loss efficiency

Intervention Details

Type: supplement
Dosage: 2 g/L in drinking water
Duration: 11 weeks

Evidence from Studies

Contradicting (0)

0
No contradicting evidence found