When fat cells get inflamed and stressed, they don't respond to signals properly, making it harder to lose fat. NAC can help reduce this inflammation and improve fat loss.
Scientific Claim
In obesity, adipose tissue inflammation and oxidative stress impair insulin signaling, leading to reduced fat loss efficiency; NAC supplementation reduces inflammatory markers and oxidative stress in adipose tissue, improving metabolic function.
Original Statement
“Fat loss doesn't stall because calories suddenly stopped working. It stalls because fat cells stop responding correctly to signals. If you watch my channel a lot, this is something I say frequently, okay? in obesity and in like stubborn belly fat scenarios, fat tissue becomes inflamed, reactive oxygen species increase, insulin signaling becomes distorted. And there was a study that was published in pharmaceutical research. It looked at this like pretty much directly. Okay, it was rodent model. They gave mice a highfat diet, but they were given NAC in their drinking water for 11 weeks. The NAC treated mice gained roughly half as much weight as the highfat diet mice without NAC, 22% versus 47%.”
Context Details
Domain
nutrition
Population
animal
Subject
adipose tissue inflammation and oxidative stress
Action
impair
Target
insulin signaling and fat loss efficiency
Intervention Details
Evidence from Studies
Supporting (1)
N-acetylcysteine Protects Mice from High Fat Diet-induced Metabolic Disorders