The Claim
In older adults with Alzheimer's disease, daily supplementation with 20 grams of creatine monohydrate for eight weeks is associated with a small but statistically significant increase in leg muscle cross-sectional area, with rectus femoris increasing from 7.6 to 7.8 cm² and vastus medialis from 10.1 to 10.2 cm².
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In older adults with Alzheimer's disease, taking 20 grams of creatine monohydrate daily for eight weeks is associated with a small increase in the size of leg muscles, specifically the rectus femoris and vastus medialis.
See the scientific wording
In older adults with Alzheimer's disease, daily supplementation with 20 grams of creatine monohydrate for eight weeks is associated with a small but statistically significant increase in leg muscle cross-sectional area, with rectus femoris increasing from 7.6 to 7.8 cm² and vastus medialis from 10.1 to 10.2 cm², suggesting a potential role in mitigating muscle atrophy in this population.
Creatine pulls water into muscle cells, making them swell, which signals the cells to build more protein and stop breaking down muscle tissue. More creatine also helps make more energy, allowing muscles to work harder and stay bigger.
What the research says
1 studyIn a small study, older adults with Alzheimer's who took 20 grams of creatine daily for eight weeks saw their leg muscles get just a tiny bit bigger, which might help slow muscle loss from the disease.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.