In older adults with low selenium levels, taking 200 micrograms of selenium and 200 milligrams of coenzyme Q10 daily for four years is associated with an increase in free triiodothyronine and a decrease in free thyroxine, indicating a change in thyroid hormone conversion that may influence metabolic and cardiovascular health.

65

Pro

0

Against

Evidence from Studies

Supporting (1)

65

Community contributions welcome

65

Supplementation with selenium and coenzyme Q10 in an elderly Swedish population low in selenium — positive effects on thyroid hormones, cardiovascular mortality, and quality of life

Randomized Controlled Trial

Human

2024 May 7

In older people with low selenium, taking selenium and CoQ10 daily for four years helped their bodies turn more of the inactive thyroid hormone (T4) into the active one (T3), which may help their metabolism and heart health.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Supplementation with selenium and coenzyme Q10 in an elderly Swedish population low in selenium — positive effects on thyroid hormones, cardiovascular mortality, and quality of life

Score: 65

DOI: 10.1186/s12916-024-03411-1

Similar Assertions

In older adults with low selenium levels, taking selenium and coenzyme Q10 supplements is associated with higher levels of reverse T3, a thyroid hormone metabolite, which may indicate a biological adjustment to lower metabolic activity.

65

0

87%

In older adults with low selenium levels, low levels of the thyroid hormone fT3 are linked to poorer mental and physical well-being. Taking selenium and coenzyme Q10 supplements removes this link and improves energy levels, reduces bodily pain, and enhances social functioning.

65

0

81%

In older adults with low selenium levels, taking selenium and coenzyme Q10 supplements for four years results in a smaller rise in thyroid-stimulating hormone (TSH) levels compared to taking a placebo, and fewer people reach the TSH level that defines subclinical hypothyroidism.

65

0

78%

In older adults with low selenium levels, higher baseline TSH levels are linked to a 35% increased risk of dying from cardiovascular disease over 10 years. Taking selenium and coenzyme Q10 supplements appears to remove this increased risk.

65

0

76%

In adults with Graves' disease taking antithyroid medication, taking selenium supplements at 100–300 μg per day for 3 to 6 months lowers levels of FT3 and FT4 hormones in the blood, but these reductions do not remain after 9 months of treatment.

39

0

76%