The Claim
In aged male mice, apigenin supplementation at 50 mg/kg/day for nine months is associated with increased activity of mitochondrial respiratory chain complexes I, II, and IV, elevated ATP levels, and improved mitochondrial membrane potential.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In older male mice, daily apigenin supplementation for nine months is associated with higher activity of key mitochondrial energy-producing complexes, increased ATP production, and stronger mitochondrial membrane potential.
See the scientific wording
In aged male mice, apigenin supplementation at 50 mg/kg/day for nine months is associated with increased activity of mitochondrial respiratory chain complexes I, II, and IV, elevated ATP levels, and improved mitochondrial membrane potential, suggesting enhanced mitochondrial energy production.
Apigenin lowers harmful molecules in muscle cells that damage mitochondria, which allows more mitochondria to form and work better. This increases the number of energy-producing parts inside mitochondria, strengthens their internal electrical charge, and makes more energy available for the cell.
What the research says
1 studyIn older male mice, giving apigenin made their muscle cells’ energy factories work better, producing more energy and becoming more numerous, which helped the mice move stronger and longer.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.