The Claim
Daily oral supplementation with 50 mg/kg of apigenin for nine months in aged male mice is associated with increased muscle mass, improved grip strength, enhanced running endurance, and elevated mitochondrial number and volume in skeletal muscle.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In aged male mice, taking 50 mg/kg of apigenin daily for nine months is linked to greater muscle mass, stronger grip strength, better running endurance, and more mitochondria in muscle tissue.
See the scientific wording
In aged male mice, daily oral supplementation with 50 mg/kg of apigenin for nine months is associated with improved muscle mass, grip strength, and running endurance, along with increased mitochondrial number and volume in skeletal muscle, suggesting a potential role in mitigating age-related muscle atrophy.
Apigenin lowers harmful molecules in muscle cells that damage mitochondria, which allows more mitochondria to form and work better. It also stops the cell from breaking down too many mitochondria and prevents muscle cells from dying, leading to stronger, more enduring muscles.
What the research says
1 studyIn older male mice, giving them apigenin every day for nine months made their muscles stronger, helped them run farther, and gave them more energy-producing parts (mitochondria) in their muscles, which likely helps slow down muscle loss from aging.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.