The Claim
In older men performing resistance training, HMB-free acid supplementation is associated with a transient increase in muscle protein synthesis during the first two weeks of training, with no significant difference from placebo at later time points.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In older men doing strength training, taking HMB-free acid may temporarily boost muscle protein synthesis in the first two weeks, but this effect disappears after that and is not different from taking a placebo.
See the scientific wording
In older men performing resistance training, HMB-free acid supplementation is associated with a transient increase in muscle protein synthesis during the first two weeks of training, but this effect is not sustained and does not differ significantly from placebo at later time points.
What the research says
1 studyIn older men doing weight training, HMB-free acid made muscles build protein a bit faster in the first two weeks, but after that, it worked no better than a sugar pill. So yes, the boost is short-lived.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.