The Claim
Testosterone-replacement therapy has no statistically significant effect on the risk of myocardial infarction in middle-aged and older men with low testosterone after at least 12 months of treatment, with a relative risk of 0.94 (95% CI 0.69–1.28).
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In middle-aged and older men with low testosterone, testosterone-replacement therapy does not change the risk of heart attack compared to placebo after 12 months of treatment.
See the scientific wording
Testosterone-replacement therapy does not significantly affect the risk of myocardial infarction in middle-aged and older men with low testosterone, with a relative risk of 0.94 (95% CI 0.69–1.28), indicating no statistically significant benefit or harm compared to placebo after at least 12 months of treatment.
Adding testosterone back into the body does not change how blood vessels form plaques or how clots form in the heart arteries, so the chance of a heart attack stays the same.
What the research says
1 studyIn older men with low testosterone, taking testosterone therapy doesn't seem to make heart attacks more or less likely, based on a big review of 23 studies. The numbers show no clear increase or decrease in heart attacks.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.