The Claim
In women aged 80–92 years with malnutrition, 3 weeks of citrulline supplementation (10 g/day) was associated with a significant increase in lean mass (mean +1.7 kg) and appendicular skeletal muscle mass (mean +1.1 kg), and a significant decrease in fat mass (mean -1.3 kg), compared to baseline.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In older women with malnutrition, taking 10 grams of citrulline daily for 3 weeks resulted in an average increase of 1.7 kilograms in lean mass and 1.1 kilograms in arm and leg muscle mass, along with an average loss of 1.3 kilograms in fat mass.
See the scientific wording
In women aged 80–92 years with malnutrition, 3 weeks of citrulline supplementation (10 g/day) was associated with a significant increase in lean mass (mean +1.7 kg) and appendicular skeletal muscle mass (mean +1.1 kg), and a significant decrease in fat mass (mean -1.3 kg), compared to baseline.
Citrulline turns into arginine in the body, which boosts the production of nitric oxide and signals muscle cells to build more protein while slowing down fat storage, leading to more muscle and less fat over time.
What the research says
1 studyIn older women who weren’t eating enough, taking 10 grams of citrulline daily for 3 weeks helped them gain muscle and lose a little fat — but this didn’t happen in men or the whole group. The study found this effect clearly in women.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.