In people with obesity from China, the genes that make a specific inflammatory marker called TNF-alpha are more active in the fat around the organs inside the belly than in the fat under the skin.

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Against

Evidence from Studies

Supporting (1)

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Comparison of gene transcription between subcutaneous and visceral adipose tissue in Chinese adults.

Cross-Sectional Study

Human

2009

The researchers compared the activity of the TNF-alpha gene in belly fat versus under-skin fat in obese Chinese adults and found it was significantly higher in belly fat, which exactly matches what the claim states.

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No contradicting evidence found

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Source Study

Comparison of gene transcription between subcutaneous and visceral adipose tissue in Chinese adults.

Score: 27

DOI: 10.1507/ENDOCRJ.K09E-091

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