The Claim

In adults with high cardiovascular risk, phase angle is significantly inversely correlated with age and positively correlated with estimated glomerular filtration rate (eGFR), but not correlated with LDL cholesterol levels.

Source: No association between LDL cholesterol levels and cellular membrane integrity assessed with phase angle: Insights from the MALIPID study.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
37score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In adults at high risk for heart disease, phase angle decreases with older age and increases with better kidney function, but does not change with LDL cholesterol levels.

See the scientific wording

In adults with high cardiovascular risk, phase angle is significantly inversely correlated with age and positively correlated with estimated glomerular filtration rate (eGFR), but not with LDL cholesterol levels, indicating that age and kidney function are stronger determinants of cellular membrane integrity than LDL-C in this population.

Why this might work

As people get older, their cells lose the ability to maintain healthy membranes, and when kidneys don't filter blood well, toxins build up and damage those same membranes. Cholesterol levels don't affect this process.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: No association between LDL cholesterol levels and cellular membrane integrity assessed with phase angle: Insights from the MALIPID study.

    In people at high risk for heart disease, older age and worse kidney function are linked to weaker cell membranes, but cholesterol levels aren’t — even very low cholesterol doesn’t hurt membrane health.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.