The Claim

In overweight and obese adults, vitamin D status is associated with resting metabolic rate per kilogram of body weight, and this association is mediated by vitamin D receptor gene expression but not by PGC-1α gene expression.

Source: Vitamin D Status and Resting Metabolic Rate May Modify through Expression of Vitamin D Receptor and Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene in Overweight and Obese Adults

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
44score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

In people who are overweight or obese, having more vitamin D in their body seems to be linked to how many calories they burn at rest, and this link happens because of how their body uses the vitamin D receptor gene — but not because of the PGC-1α gene.

See the scientific wording

In overweight and obese adults, vitamin D status is associated with resting metabolic rate per kilogram of body weight, and this association is mediated by vitamin D receptor gene expression, but not by PGC-1α gene expression.

What the research says

1 study

  1. Study: Vitamin D Status and Resting Metabolic Rate May Modify through Expression of Vitamin D Receptor and Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene in Overweight and Obese Adults

    This study found that in overweight and obese people, vitamin D levels affect how many calories the body burns at rest through the vitamin D receptor gene, but not through the PGC-1α gene — just like the claim said.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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