mechanistic
Analysis v1
Strong Support

In people who are overweight or obese, having more vitamin D in their body seems to be linked to how many calories they burn at rest, and this link happens because of how their body uses the vitamin D receptor gene — but not because of the PGC-1α gene.

46
Pro
0
Against

Evidence from Studies

Supporting (1)

46

Community contributions welcome

This study found that in overweight and obese people, vitamin D levels affect how many calories the body burns at rest through the vitamin D receptor gene, but not through the PGC-1α gene — just like the claim said.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.