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Strong Opposition

If you're an obese adult with fatty liver, how much folate is in your blood might help explain how much fat is in your liver — and it could account for nearly 1 in 5 cases, even after considering body weight.

0
Pro
44
Against

Evidence from Studies

Supporting (0)

0

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No supporting evidence found

Contradicting (1)

44

Community contributions welcome

44

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.

Cross-Sectional Study
Human
2018 Mar 6

The study shows that a low-carb diet can increase folate and reduce liver fat, but it doesn’t prove that folate levels explain 19.5% of liver fat changes after accounting for body weight like the claim says.

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.

Score: 44
DOI: 10.1016/j.cmet.2018.01.005

Similar Assertions

Eating fewer carbs and more protein for a week might help turn off fat-making genes and turn on fat-burning and metabolism genes in the livers of obese people with fatty liver disease.

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If you're an obese adult with fatty liver disease, switching to a low-carb, higher-protein diet for just two weeks might quickly boost good gut bacteria that make folate—and your blood folate levels could go up in as little as one day.

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If you're an obese adult with fatty liver disease, switching to a very low-carb, high-fat diet for just two weeks might cut your liver fat by nearly half—and you could see improvements in as little as one day.

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Eating too much fructose—like the sugar in soda and sweet snacks—can make liver scarring worse if you already have fatty liver disease, but cutting back on fructose can help your liver get healthier.

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People with NAFLD—where fat builds up in the liver without drinking alcohol—often also have issues like being overweight, having high blood sugar, or other metabolic problems.

0
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