The Claim
In obese adults, adipose tissue hormone-sensitive lipase (HSL) and lipoprotein lipase (LPL) exhibit no increase in enzymatic activity in response to postprandial insulin, and this lack of response may contribute to altered lipoprotein metabolism and an elevated risk of coronary heart disease.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In people with obesity, fat tissue does not increase the activity of two key enzymes—HSL and LPL—after eating, which may lead to abnormal fat processing in the blood and a higher chance of developing coronary heart disease.
See the scientific wording
In obese adults, adipose tissue hormone-sensitive lipase (HSL) and lipoprotein lipase (LPL) do not increase activity in response to postprandial insulin, which may contribute to altered lipoprotein metabolism and increased risk of coronary heart disease.
In obese people, after eating, the hormone insulin doesn't properly tell fat cells to stop breaking down fat or to clear fat from the blood. This means too much fat stays in the bloodstream, which can lead to unhealthy fat buildup and increase the chance of heart disease.
What the research says
1 studyStudy: Adipose tissue metabolism in obesity: lipase action in vivo before and after a mixed meal.
In obese people, their fat cells don’t respond properly to the insulin spike after eating, so they can’t break down fat the way they should. This might lead to unhealthy fat buildup and raise the risk of heart disease.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.