The Claim
In adults with resistance to thyroid hormone β, TRIAC therapy is associated with a reduction in resting energy expenditure toward normal levels, with a Z-score change from +1.3 to +0.89 (P = .38), indicating a non-significant trend.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In adults with resistance to thyroid hormone β, treatment with TRIAC is associated with a decrease in resting energy expenditure toward normal values, though the change was not statistically significant.
See the scientific wording
In adults with resistance to thyroid hormone β, TRIAC therapy is associated with a reduction in resting energy expenditure toward normal levels, though the change did not reach statistical significance (Z-score from +1.3 to +0.89, P = .38), suggesting a possible but unconfirmed effect on metabolic rate.
TRIAC activates thyroid hormone receptors in the brain that control hormone production, causing the thyroid gland to make less thyroid hormone. With less thyroid hormone in the blood, the body's tissues burn less energy at rest, lowering the metabolic rate.
What the research says
1 studyIn people with a rare condition where the body doesn’t respond properly to thyroid hormones, a treatment called TRIAC helped lower their unusually high metabolism a little bit — but not enough to be 100% sure it was the medicine and not just chance.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.