Stimulating the vagus nerve might lower a marker of inflammation called CRP in people who are acutely sick, but the evidence is shaky because the studies were small and mixed, so we can't say it works for long-term inflammation.

Scientists have looked at 36 studies on a treatment that stimulates the vagus nerve to reduce inflammation, but the studies are too different and poorly done to say for sure if it actually works for any specific condition.

Doctors think stimulating the vagus nerve might reduce inflammation in the body, but we don't have solid proof yet — we need better studies to find out if it really works.

For people with psoriatic arthritis who are feeling better, using a small device on the skin to stimulate a nerve in the neck for five days may help lower inflammation markers and improve how they feel, even if other common measures of arthritis don’t change.