The Claim

Creatine supplementation at a dosage of 0.14 g/kg/day combined with resistance training for two years increases lean tissue mass in postmenopausal women who complete the full intervention, but no increase in lean tissue mass is observed in intent-to-treat analyses due to low compliance.

Source: A 2-yr Randomized Controlled Trial on Creatine Supplementation during Exercise for Postmenopausal Bone Health

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
72score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Postmenopausal women who take 0.14 grams of creatine per kilogram of body weight daily and complete two years of resistance training gain more lean tissue mass than those who do not, but this gain is not seen in all women who start the program because many do not finish it.

See the scientific wording

Creatine supplementation (0.14 g/kg/day) for two years with resistance training increases lean tissue mass in postmenopausal women who complete the full intervention, but this effect is not observed in intent-to-treat analyses due to low compliance.

Why this might work

Creatine enters muscle cells and is converted into a high-energy molecule that helps make more ATP, the fuel for muscle contractions. This extra energy allows muscles to work harder during training, which triggers the body to build more muscle protein and increase muscle size over time.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: A 2-yr Randomized Controlled Trial on Creatine Supplementation during Exercise for Postmenopausal Bone Health

    In women who took creatine and stuck to the exercise plan for two years, they gained a little more muscle than those who took a placebo. But in the whole group, many people didn’t take the creatine regularly, so the overall benefit wasn’t visible — which matches the claim.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.