The Claim
In the isolated-perfused rat liver, L-triiodothyronine (T3) increases urea production alongside glucose production.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In a laboratory setup using rat livers, the hormone T3 causes both urea and glucose production to rise at the same time.
See the scientific wording
In the isolated-perfused rat liver, L-triiodothyronine (T3) increases urea production alongside glucose production, suggesting coordinated stimulation of gluconeogenesis and amino acid nitrogen disposal.
T3 causes the liver to take in more amino acids from the blood, uses those amino acids to make glucose, and simultaneously converts the leftover nitrogen from those amino acids into urea for removal. This happens because T3 boosts energy production in the liver's powerhouses, which fuels both glucose-making and nitrogen-processing reactions at the same time.
What the research says
1 studyIn a lab-tested rat liver, T3 hormone makes the liver use more amino acids to make glucose, and since amino acids contain nitrogen, the liver must also get rid of that nitrogen by turning it into urea — so both glucose and urea production go up together.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.