The Claim

In adults with severe burn injuries covering 25–50% of total body surface area, daily administration of human growth hormone at 0.1 mg/kg/day for 7–10 days post-injury is associated with a higher incidence of hyperglycemia (100% of patients) and elevated metabolic rates (178% of predicted normal) compared to oxandrolone or no treatment, despite similar improvements in weight retention and wound healing.

Source: Comparison of the anabolic effects and complications of human growth hormone and the testosterone analog, oxandrolone, after severe burn injury.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
55score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In adults with severe burns covering 25–50% of their body, daily human growth hormone treatment for 7–10 days results in hyperglycemia in all patients and increases metabolic rates to 178% of normal compared to oxandrolone or no treatment, while weight retention and wound healing are similar across groups.

See the scientific wording

In adults with severe burn injuries covering at least 25–50% of total body surface area, daily administration of human growth hormone at 0.1 mg/kg/day for 7–10 days post-injury is associated with a higher incidence of hyperglycemia (100% of patients) and elevated metabolic rates (178% of predicted normal) compared to oxandrolone or no treatment, despite similar improvements in weight retention and wound healing.

Why this might work

Human growth hormone tells the liver to make more IGF-1, which helps the body build muscle and heal wounds, but it also makes the liver ignore insulin, so it keeps making sugar even when it's not needed. This floods the blood with sugar and forces the body to burn energy faster than normal.

Verified mechanismbased on 1 study

What the research says

1 study

  1. Study: Comparison of the anabolic effects and complications of human growth hormone and the testosterone analog, oxandrolone, after severe burn injury.

    In severely burned adults, HGH shots help keep weight and heal skin just as well as another drug, but they also cause almost everyone to have high blood sugar and a super-fast metabolism — which the other drug doesn’t do.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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