In some cancers, a type of collagen (type I) tricks cells into becoming more mobile and invasive by turning off a 'stickiness' protein (E-cadherin) and turning on 'migration' proteins (N-cadherin, SNAI1).

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The Molecular Interaction of Collagen with Cell Receptors for Biological Function

Narrative Review

This study talks generally about how collagen interacts with cells and how it can be used in medicine, but it doesn't mention cancer or the specific molecules involved in the claim, so it doesn't help prove or disprove it.

Source Study

The Molecular Interaction of Collagen with Cell Receptors for Biological Function

Score: 1

DOI: 10.3390/polym14050876

Similar Assertions

In cancer, collagen binding to DDR1 receptors triggers signals that help tumor cells spread and invade other tissues, which is a key step in cancer progression.

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A specific protein on cell surfaces called α1β1 integrin sticks to certain types of collagen and tells cells to grow, make repair enzymes, and produce more collagen.

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