In the thyroid gland, iodine levels differ greatly from one follicle to another, while selenium and zinc levels remain relatively consistent across follicles, suggesting iodine is actively regulated in a variable way, whereas selenium and zinc are distributed more evenly.

35

Pro

0

Against

Evidence from Studies

Supporting (1)

35

Community contributions welcome

35

The TSH-Dependent Variation of the Essential Elements Iodine, Selenium and Zinc within Human Thyroid Tissues

Cross-Sectional Study

Human

The study found that iodine levels in the thyroid change a lot from one tiny gland unit to another, while selenium and zinc stay pretty even — meaning iodine is more active and responsive, while the others are more steady.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

The TSH-Dependent Variation of the Essential Elements Iodine, Selenium and Zinc within Human Thyroid Tissues

Score: 35

DOI: 10.1016/S0946-672X(98)80006-0

Similar Assertions

In people with thyroid disease, the levels of iodine, selenium, and zinc in thyroid tissue are typically within the range seen in earlier studies, even though the general population may have slightly low levels of iodine and selenium.

35

0

82%

In patients with mild deficiencies of iodine and selenium, the levels of these elements in thyroid tissue change in ways that relate to the amount of thyroid-stimulating hormone present, suggesting that nutrient levels and thyroid activity are linked in diseased tissue.

35

0

75%