The Claim

In trained young men, acute ingestion of creatine hydrochloride (0.03 g/kg) combined with caffeine (6 mg/kg) is associated with a statistically significant increase in total resistance exercise volume during chest and leg press exercises performed to failure at 60% 1RM compared to placebo, with no significant change in serum testosterone or cortisol levels.

Source: Acute influence of mixed creatine hydrochloride and caffeine supplementation on serum levels of testosterone and cortisol, repetition sustainability and resistance exercise volume

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
39score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

In trained young men, taking creatine hydrochloride and caffeine together before a workout increases the total amount of weight lifted during chest and leg presses at 60% of their one-rep maximum, compared to a placebo, without changing blood levels of testosterone or cortisol.

See the scientific wording

In trained young men, acute ingestion of creatine hydrochloride (0.03 g/kg) combined with caffeine (6 mg/kg) is associated with a statistically significant increase in total resistance exercise volume during chest and leg press exercises performed to failure at 60% 1RM, compared to placebo, though no significant change in serum testosterone or cortisol levels was observed.

Why this might work

Creatine boosts the muscle's ability to quickly regenerate energy, letting the muscles keep working harder for longer. Caffeine makes the nerves that control muscles fire more strongly, so more muscle fibers turn on during each lift. Together, this lets a person do more total reps and weight before getting too tired.

Supported mechanismbased on 1 study

What the research says

1 study

  1. Study: Acute influence of mixed creatine hydrochloride and caffeine supplementation on serum levels of testosterone and cortisol, repetition sustainability and resistance exercise volume

    Taking creatine and caffeine together helped guys lift more total weight during their workout, but didn’t change their hormone levels — just like the claim said.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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