In women with autoimmune thyroiditis, levels of thyroid autoantibodies typically drop during pregnancy and rise again after childbirth unless selenium is taken, which may help prevent this increase.

67

Pro

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Against

Evidence from Studies

Supporting (1)

67

Community contributions welcome

67

Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the “SERENA study”, a randomized, double-blind, placebo-controlled trial

Randomized Controlled Trial

Human

2019 Dec

This study found that taking selenium supplements during pregnancy helps keep harmful thyroid antibodies low after giving birth, while women who didn’t take selenium saw their antibodies spike. So, selenium may help prevent thyroid problems after pregnancy.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the “SERENA study”, a randomized, double-blind, placebo-controlled trial

Score: 67

DOI: 10.1007/s12020-019-01958-1

Similar Assertions

Taking 83 micrograms of L-selenomethionine daily during pregnancy and for six months after childbirth is associated with lower levels of specific antibodies targeting the thyroid in women with autoimmune thyroiditis, compared to those taking a placebo.

67

0

88%

Taking selenium supplements during pregnancy does not improve or worsen the mother's well-being, pregnancy complications, or baby's health outcomes in women with autoimmune thyroiditis.

67

0

80%

Taking 83 micrograms of L-selenomethionine daily during pregnancy does not change thyroid hormone levels, thyroid size, or tissue appearance in women with autoimmune thyroiditis. This suggests the supplement affects immune markers related to the thyroid without altering thyroid structure or function.

67

0

80%

Taking selenium supplements is associated with lower levels of antibodies that attack the thyroid in people diagnosed with autoimmune thyroid disease.

72

59

76%

People with autoimmune thyroid disease who have low selenium levels tend to have higher levels of certain antibodies that target the thyroid, compared to those with normal selenium levels.

50

0

72%