If a guy new to lifting weights gets a bigger muscle swell right after his first workout, he’s likely to gain more muscle over the next 6 weeks.

Swelling in muscles right after a light weight workout does not indicate whether those muscles will grow larger over the next eight weeks of similar training.

Muscle swelling induced by resistance training may persist for up to 72 hours post-exercise, potentially confounding hypertrophy measurements if assessed within this window.

Among men who regularly lift weights and train their legs twice a week for 8 weeks, doing about 12 sets per week leads to the same gains in muscle size and lean mass as doing 30% or 60% more sets, suggesting that increasing volume beyond this point does not result in greater muscle growth.

Muscle swelling following resistance training returns to baseline within 24 hours, regardless of training volume (7–21 sets per session).

If you're someone who's been lifting weights for a while, doing the same amount of heavy training over 9 weeks will make your thigh muscles grow by about half a centimeter — whether you spread your workouts over 2 or 4 days a week.