The Claim
Inactivation of the myostatin gene results in increased skeletal muscle mass in humans.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When the myostatin gene is turned off in humans, skeletal muscle mass increases.
See the scientific wording
Inactivation of the myostatin gene leads to increased skeletal muscle mass in humans.
When the myostatin gene is turned off, muscles grow larger because the signal that normally stops them from growing is removed. This allows muscle cells to make more proteins and multiply, causing individual muscle fibers to thicken and the overall muscle to get bigger.
What the research says
3 studiesWhen scientists blocked a gene called myostatin with a drug, people’s muscles got bigger — just like the claim says. Turning off myostatin lets muscles grow more.
When scientists turned off the myostatin gene in mice, the mice grew bigger, stronger muscles. This suggests that doing the same thing in humans would likely make muscles bigger too.
Study: Modulating skeletal muscle mass by postnatal, muscle‐specific inactivation of the myostatin gene
When scientists turned off the myostatin gene in mice, their muscles got much bigger—exactly what the claim says would happen in humans. This suggests that turning off this gene in people could also make muscles grow larger.
Related videos
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 3 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.