Resting longer between sets lets you lift more total weight, which makes muscles grow bigger.
Evidence from Studies
Supporting (3)
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The Effect of Resistive Exercise Rest Interval on Hormonal Response, Strength, and Hypertrophy With Training
People who rested longer between weightlifting sets grew their muscles more than those who rested briefly, even though both groups got equally stronger. This suggests taking more time to recover between sets helps muscles grow bigger.
Increased Neuromuscular Activity, Force Output, and Resistance Exercise Volume When Using 5-Minute Compared with 2-Minute Rest Intervals Between the Sets
Longer breaks between weightlifting sets let you lift more total weight and feel less tired, which helps your muscles grow better — and this study proved it.
Time under tension and mechanical variables in the bench press exercise at different rest intervals
When lifters took longer breaks between sets, they could do more reps and lift more total weight, which means their muscles were under more stress — and that’s exactly what helps muscles grow.
Contradicting (2)
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Give it a rest: a systematic review with Bayesian meta-analysis on the effect of inter-set rest interval duration on muscle hypertrophy
The study found that resting longer between sets doesn’t really help you build more muscle than resting a bit shorter — and it might even mean you do fewer reps, which could hurt muscle growth. So, the idea that longer rests make you grow more by increasing effort doesn’t hold up.
The Effect of Inter-Set Rest Intervals on Resistance Exercise-Induced Muscle Hypertrophy
The study found that taking longer breaks between weightlifting sets doesn’t hurt muscle growth — and might even help — which goes against the idea that you need short breaks to build more muscle.