mechanistic
Analysis v1
Strong Support
Insulin helps a cellular pump work better when fuel levels are low, but doesn’t make it go faster when everything’s already maxed out — it’s like giving the pump a sensitivity boost, not a power upgrade.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
10
Effect of insulin upon membrane‐bound (Na+ + K+)‐ATPase extracted from frog skeletal muscle.
Cross-Sectional Study
Animal
1975 OctThe study shows insulin boosts a cellular pump in frog muscle when fuel levels are low, but not when they’re high, suggesting insulin makes the pump more sensitive to its fuels rather than making it work faster overall.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.