The Claim
Insulin enhances the activity of membrane-bound (Na+ + K+)-ATPase in isolated frog skeletal muscle membranes, with stimulation ranging from 9.8% to 53% under physiological ion and ATP concentrations (25 mM Na+, 10 mM K+, 2 mM ATP), and up to 400% under low Na+ (4 mM) and low ATP (0.5 mM) conditions, indicating a context-dependent modulation of enzyme activity by insulin.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
Insulin can boost a tiny cellular pump in frog muscle cells, and it works way better when certain conditions like low salt or energy levels are present.
See the scientific wording
Insulin increases the activity of membrane-bound (Na+ + K+)-ATPase in isolated frog skeletal muscle membranes by 9.8% to 53% under physiological ion and ATP concentrations (25 mM Na+, 10 mM K+, 2 mM ATP), with stimulation reaching up to 400% under low Na+ (4 mM) and low ATP (0.5 mM) conditions, indicating that insulin enhances enzyme activity in a context-dependent manner.
What the research says
1 studyStudy: Effect of insulin upon membrane‐bound (Na+ + K+)‐ATPase extracted from frog skeletal muscle.
The study shows that insulin boosts a key enzyme in frog muscle cells, especially when sodium and energy levels are low, just like the claim says.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.